Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.
Build and analyze phylogenetic trees using MAFFT (multiple alignment), IQ-TREE 2 (maximum likelihood), and FastTree (fast NJ/ML). Visualize with ETE3 or FigTree. For evolutionary analysis, microbial genomics, viral phylodynamics, protein family analysis, and molecular clock studies.
Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.
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New: K-Dense BYOK — A free, open-source AI co-scientist that runs on your desktop, powered by Claude Scientific Skills. Bring your own API keys, pick from 40+ models, and get a full research workspace with web search, file handling, 250+ scientific databases, and access to all 170+ skills in this repo. Your data stays on your computer, and you can optionally scale to cloud compute via Modal for heavy workloads. Get started here.
A comprehensive collection of 170+ ready-to-use scientific and research skills (now including cancer genomics, drug-target binding, molecular dynamics, RNA velocity, geospatial science, time series forecasting, FRED economic data, and more) for any AI agent that supports the open Agent Skills standard, created by K-Dense. Works with Cursor, Claude Code, Codex, and more. Transform your AI agent into a research assistant capable of executing complex multi-step scientific workflows across biology, chemistry, medicine, and beyond.
The demo above shows K-Dense Web — the hosted platform built on top of these skills. Claude Scientific Skills is the open-source skill collection; K-Dense Web is the full AI co-scientist platform with more power and zero setup.
These skills enable your AI agent to seamlessly work with specialized scientific libraries, databases, and tools across multiple scientific domains. While the agent can use any Python package or API on its own, these explicitly defined skills provide curated documentation and examples that make it significantly stronger and more reliable for the workflows below:
npx claudepluginhub drhabui/claude-scientific-skillsComprehensive skill pack with 66 specialized skills for full-stack developers: 12 language experts (Python, TypeScript, Go, Rust, C++, Swift, Kotlin, C#, PHP, Java, SQL, JavaScript), 10 backend frameworks, 6 frontend/mobile, plus infrastructure, DevOps, security, and testing. Features progressive disclosure architecture for 50% faster loading.
This skill should be used when users need to generate ideas, explore creative solutions, or systematically brainstorm approaches to problems. Use when users request help with ideation, content planning, product features, marketing campaigns, strategic planning, creative writing, or any task requiring structured idea generation. The skill provides 30+ research-validated prompt patterns across 14 categories with exact templates, success metrics, and domain-specific applications.
Develop, test, build, and deploy Godot 4.x games with Claude Code. Includes GdUnit4 testing, web/desktop exports, CI/CD pipelines, and deployment to Vercel/GitHub Pages/itch.io.
A growing collection of Claude-compatible academic workflow bundles. Covers scientific figures, manuscript writing and polishing, reviewer assessment, citation retrieval, data availability, paper reading, literature search, response letters, paper-to-PPTX conversion, and evidence-grounded Chinese invention patent drafting. Rules are organized as reusable skill folders with explicit workflows and quality checks.
Upstash Context7 MCP server for up-to-date documentation lookup. Pull version-specific documentation and code examples directly from source repositories into your LLM context.
Consult multiple AI coding agents (Gemini, OpenAI, Grok, Perplexity, plus codex and antigravity CLIs when installed) to get diverse perspectives on coding problems